“How do you eat DNA spaghetti?”
You use a replication fork. -Anonymous
Hello
and welcome to the blog!
My
name is Angela Hemesath. As a senior at BASIS Scottsdale in Arizona, I am
participating in one of BASIS’s unique programs: the Senior Research Project.
The Senior Research Project (SRP) is an opportunity for BASIS Seniors to use
their third trimester to explore a research question through an internship.
With
the help of my Faculty Adviser, Mr. John Nishan, and my On-Site Mentors, Dr. Dan
Riggs, Mrs. Victoria Garbitt, and Dr. P. Leif Bergsagel, I have been given the opportunity to intern at the Mayo Clinic in
Scottsdale (linked on the right). My research will focus largely on the genetic
components of Multiple Myeloma, a cancer of the plasma cells (“Diseases and
Conditions Multiple Myeloma”). Studies have shown that the malfunction of a
certain gene, called the MYC gene, may be heavily involved in causing Multiple Myeloma
(Dib). Through my work at the lab, I hope to answer the following questions: “Can
the distance of one gene indeed affect another? Is multiple myeloma actually
caused by the translocation and subsequent dysregulation of the MYC gene? Will
a genetic study of medicine lead to individualized care?”
I
hope you follow me on my journey and I hope that I can entertain you a little
along the way!
Best
wishes,
Angela
Hemesath
If
you’d like to read more on my SRP, my proposal is linked on the right.
Sources:
Dib, Amel, Ana Gabrea, Oleg K. Glebov, P. Leif Bergsagel, and W. Michael Kuehl. “Characterization
of MYC Translocations in Multiple Myeloma Cell Lines.” Nih.com. NCBI,
3 Sep. 2009. Web. 16 Dec. 2014.
“Diseases and Conditions Multiple Myeloma.” Mayoclinic.org.
Mayo Clinic, n.d. Web. Oct. 2014.
